10/24/19 - 9:45 AM to 11:00 AM
Department Seminar: Professor Catherine L. Grimes
Professor Catherine Grimes' lab is generally interested in understanding how mammalian cells recognize and respond to the presence of a pathogen. Researchers take a chemical biological approach to investigate this problem, utilizing a host of tools such as organic synthesis, molecular biology, biochemistry and bacterial cell engineering. They study the activation of the innate immune system by a bacterial threat. The innate immune system is the body's first line of defense against invading pathogens. This ancient system has evolved to live in a symbiotic relationship with some commensal bacteria and at the same time recognize and destroy virulent bacteria. Understanding the molecular details of this system is extremely important, as chronic inflammatory disorders, such as Inflammatory Bowel Disease, arise from an inappropriate immune response to bacteria.
Professor Grimes earned her bachelor's degree in chemistry from Villanova University, her master's in chemistry from Princeton University, and her doctorate in chemistry from Harvard University. She was a Cancer Research Institute Post-doctoral Fellow at Harvard University and Massachusetts General Hospital. She joined the faculty at the University of Delaware in 2011, and holds appointments in both the Department of Chemistry and Biochemistry and the Department of Biological Sciences.