10/06/16 -9:45 AM to 11:00 AM
Department Seminar: Professor Marisa Kozlowski
"Oxygen Driven Fragment Coupling by Activation of C-H, N-H, and O-H Bonds"
Professor Marisa Kozlowski received a bachelor’s degree in chemistry from Cornell University in 1989, and earned her doctorate from the University of California at Berkeley in 1994 for work on the rational design of enzyme inhibitors under the direction of Paul Bartlett. After studying asymmetric catalysis in the laboratories of David A. Evans at Harvard University as a National Science Foundation post-doctoral fellow, she joined the faculty at the University of Pennsylvania in 1997. She currently holds the rank of professor.
The major focus of Professor Kozlowski's research is the development of new catalytic methods for efficient organic synthesis using computation and high throughout screening.As well as using traditional screening and development approaches, her group employs several novel computational tools for the discovery and optimization of new reagents and catalysts. These new synthetic methods comprise the key steps in our total synthesis strategies to a variety of important pharmaceutical agents and natural products. Research highlights include the asymmetric oxidative C-C bond forming reactions; aeactions of α-ketoesters and derivatives; and computer-aided design of chiral auxiliaries and catalysts.
Her contributions have been recognized by a DuPont Young Investigator Award in 1998, a National Science Foundation CAREER Award in 2001, an Alfred P. Sloan Research Fellowship, the Kahn Award for Distinguished Teaching by an Assistant Professor at the University of Pennsylvania, an American Cancer Society Beginning Research Scholar Award in 2002, an American Chemical Society(ACS) Travel Progress Award in 2007, the Philadelphia Organic Chemists’ Club Award in 2010, election as a Fellow of the American Association for the Advancement of Science in 2012, the Philadelphia ACS Section Award in 2012, and election as an American Chemical Society Fellow in 2013. In addition to more than 100 independent publications, Professor Kozlowski co-authored with Professor Patrick Walsh the book, “Fundamentals of Asymmetric Catalysis.” She has served on numerous study sections including a term as chair of the American Cancer Society CDD Study Section. She is currently a member of the Organic Reactions Editorial Board and an associate editor for the Journal of Organic Chemistry.