04/19/18 -9:45 AM to 11:00 AM
Kolthoff Lectureship: Professor Carlos José Bustamante
Izaak M. Kolthoff Lectureship in Chemistry
Professor Carlos José Bustamante is a Howard Hughes Medical Institute (HHMI) investigator and professor of molecular and cell biology, physics, and chemistry at the University of California, Berkeley, a position he has held since 1998. He received his bachelor’s degree from the Universidad Peruana Cayetano Heredia in Lima, his masters in biochemistry from the Universidad Nacional Mayor de San Marcos in Lima, and his doctorate in biophysics from University of California, Berkeley, where he studied with Ignacio Tinoco Jr. As a post-doctoral fellow at the Lawrence Berkeley National Laboratory, Bustamante studied with Marcos Maestre. Before moving to Berkeley, he was an HHMI investigator at the University of Oregon. He is a Fellow of the National Academy of Sciences.
Professor Bustamante’s laboratory develops and applies novel methods of single-molecule manipulation and detection, such as optical tweezers, single-molecule fluorescence microscopy, and super-resolution microscopy. These techniques are used to understand:
- DNA packaging into bacteriophage Φ29 capsids;
- translation and protein folding;
- protein degradation by ClpXP;
- mitochondrial fission, and
- catalysis-enhanced enzyme diffusion
His group is affiliated with the departments of Molecular and Cell Biology, Physics, and Chemistry as well as the Physical Biosciences Division at Lawrence Berkeley National Laboratory.
Kolthoff Lectureship in Chemistry
Izaak Maurits Kolthoff was born on February 11, 1894, in Almelo, Holland. He died on March 4, 1993, in St. Paul, Minnesota. In 1911, he entered the University of Utrecht, Holland. He published his first paper on acid titrations in 1915. On the basis of his world-renowned reputation, he was invited to join the faculty of the University of Minnesota’s Department of Chemistry in 1927. By the time of his retirement from the University in 1962, he had published approximately 800 papers. He continued to publish approximately 150 more papers until his health failed. His research, covering approximately a dozen areas of chemistry, was recognized by many medals and memberships in learned societies throughout the world, including the National Academy of Sciences and the Nichols Medal of the American Chemical Society. Best known to the general public is his work on synthetic rubber. During World War II, the government established a comprehensive research program at major industrial companies and several universities, including Minnesota. Kolthoff quickly assembled a large research group and made major contributions to the program. Many of Kolthoff’s graduate students went on to successful careers in industry and academic life and, in turn, trained many more. In 1982, it was estimated that approximately 1,100 Ph.D. holders could trace their scientific roots to Kolthoff. When the American Chemical Society inaugurated an award for excellence in 1983, he was the first recipient.