10/18/18 - 9:45 AM to 10:45 AM
Special Seminar: Dmitry Koltun, Ph.D.
Design and Synthesis of Potent and Selective CaMKII Inhibitor GS-122 and Late Current-Selective Sodium Channel Blockers
The problem of selectivity towards a given biological target is one of the central problems of modern drug discovery. In this talk, selectivity problems and successful solutions will be discussed using ion channel blockers and kinase inhibitors as examples.