03/26/19 - 9:45 AM to 10:45 AM
Student Seminar Series: Professor Christina Woo
Student Seminar Series
The chemistry of binding site hotspot mapping by photo-affinity labeling
Christina M. Woo is an assistant professor in the Department of Chemistry and Chemical Biology at Harvard University, and an affiliate member of the Broad Institute. She obtained a Bachelor of Arts in chemistry from Wellesley College (2008), and conducted undergraduate research in the laboratory of Professor Dora Carrico-Moniz. She obtained her doctorate in 2013 from Yale University, under the guidance of Professor Seth B. Herzon in the synthetic and chemical biology studies of diazofluorene antitumor antibiotics. In 2013, Woo joined the laboratory of Professor Carolyn R. Bertozzi at the University of California, Berkeley, as a Jane Coffins Child post-doctoral fellow. She continued on at Stanford University (2015) as a Burroughs Wellcome Fund post-doctoral fellow, where she developed a mass-independent chemical glycoproteomics platform for the identification of non-templated post-translational modifications. She has been recognized by the Sloan Research Foundation, International Chemical Biology Society Young Chemical Biologist Award, the National Institutes of Health DP1 Avenir Award, and Ono Pharma Foundation Breakthrough Science Award.
Woo’s independent research focuses on how exogenous and endogenous small molecules influence protein function. Projects in Professor Woo's research group bridge chemistry and biology to reveal how small molecules influence proteins and human health. Current projects include developing approaches that combine chemical biology and mass spectrometry to reveal how small molecules interact with the proteome; building new tools to probe and engineer cellular pathways that use small molecules, like glycans, to modify proteins during immunoactivation; accessing unique chemical scaffolds to evaluate the regulation of protein interactions by novel mechanisms.