Nestled on the first floor of Kolthoff Hall (193 Kolthoff Hall), the LeClaire-Dow Instrumentation Facility is one of the most sophisticated, specialized instrumentation facilities on the University of Minnesota campus.

It houses the Mass Spectrometry Laboratory (MSL), the Nuclear Magnetic Resonance (NMR) Laboratory, and the X-Ray Crystallographic Laboratory (XCL). These laboratories annually support hundreds of researchers in the Department of Chemistry, across the university, and from other institutions and industries. 

The LeClaire-Dow Instrumentation Facility was supported by generous contributions from the Dow Chemical Company.